Over the past few years, the incorporation of epidermal growth factors and peptides have increased tremendously in skincare products due to their high affectivity shown by numerous clinical trials. However, in order to understand exactly how epidermal growth factors help the skin, it is important to understand what causes skin aging and damage in the first place.
The Major Causes of Negative Changes in the Skin
Skin aging is caused by a number of intrinsic and extrinsic changes inside the skin; however, the most significant of these changes are the ones that occur in the inner layer known as dermis. While the intrinsic causes of aging include the individual's genes and their body's ability to protect against free radical damage, the extrinsic causes of aging are mainly associated with environmental damage like pollution, sun exposure, and nutrition. The dermis of the skin contains all the important skin cells and fibers, which gives the skin its elasticity and strength. Skin damage is caused by the fragmentation of the fibers inside the skin and decreased production of collagen and elastin fibers – which leads to skin loosening, wrinkle formation, and roughness of the skin. (1)
How Epidermal Growth Factors Work
Epidermal growth factors are a type of peptide formed of 53 amino acids, which play an important role in the regulation of skin cells proliferation. It works by binding to the epidermal growth factor found on the plasma membrane and has been shown to promote wound healing on topical application by numerous studies.
One such study included a total of 29 participants around the age of 30 years old, with signs of photo-aging on their skin. After using an epidermal growth factor containing skin serum twice a day for 30 days, these individuals reported significant improvements in the smoothness of their skin, along with diminishing red and brown aging spots. Hence, the study concluded by proving epidermal growth factor serums to be extremely effective skincare products. (2)
Dermaesthetics’ serums are known for their anti-aging and skin healing properties due to the high concentrations of epidermal growth factors in their formulas. The top three serums include the following:
EGF/FGF Marvel Serum
The EGF/FGF Marvel Serum is a popular serum known for its potent skin healing potential due to its cell renewal properties. It is a dual skin treatment containing ingredients to support both fibroblasts and epidermal growth factors, which work together to promote the appearance of glowing, wrinkle-free, and younger-looking skin.
DNA Matrix Serum
The DNA Matrix Serum is a highly recommended anti-aging serum due to its unique ingredients, which are specifically incorporated to target signs of aging, including wrinkles, skin dullness, and photo-damage.
Intensive Wrinkle Serum
The Intensive Wrinkles Serum has proven itself to be a powerful solution that targets five signs of aging, including smile lines, crow lines, bunny lines, forehead lines, and frown lines.
- Sherratt, Michael J. "Tissue elasticity and the ageing elastic fibre." Age (Dordrecht, Netherlands) vol. 31,4 (2009): 305-25. doi:10.1007/s11357-009-9103-6
- Hardwicke, J et al. "Epidermal growth factor therapy and wound healing--past, present and future perspectives." The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland vol. 6,3 (2008): 172-7. doi:10.1016/s1479-666x(08)80114-x